What characteristic of non-keratinized stratified squamous epithelium affects water loss?

Non-keratinized stratified squamous epithelium is characterized by having less keratin compared to keratinized stratified squamous epithelium. This is significant because keratin is a protective protein that forms a tough barrier, helping to minimize water loss from underlying tissues. In non-keratinized types, the cells are more hydrated and provide a moist environment, which is essential in areas such as the oral cavity, esophagus, and vagina where moisture retention is crucial for function and protection against abrasion.

The presence of less keratin allows for greater permeability to water, which results in a higher potential for water loss in comparison to keratinized epithelium. This characteristic is critical in the physiological functions of areas where non-keratinized stratified squamous epithelium is found, as it contributes to maintaining moisture and providing resilience against environmental stress.